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Behçet’s Disease is a rare, chronic, multisystem, inflammatory disease.

Painful, recurrent oral ulcers are the most common manifestation, but genital ulcers, ocular disease, skin lesions, joint pain, and other manifestations may also occur.1,2 Without recognition of the common thread connecting these seemingly unrelated manifestations, a diagnosis can be delayed for years.3

About Behçet’s

Learn about the disease,
including manifestations, causes,
and management

Recognize Behçet’s

Understand the challenges
of diagnosing Behçet’s Disease and
the importance of referring
to a rheumatologist

Access Resources

Obtain diagnostic criteria,
view photos of disease
, and find links to
useful websites

Suspect Behçet’s disease?
Refer to a rheumatologist to confirm a diagnosis

Behçet’s (pronounced beh-CHETS) Disease, also known as Behçet’s Syndrome, was discovered in Turkey by Hulusi Behçet, a dermatologist who noted the triad of aphthous oral ulcers, genital ulcers, and recurrent eye inflammation. Behçet’s Disease is often arrived at through a differential diagnosis that rules out other possibilities. Because of this, it’s frequently misdiagnosed and can take ~5 years from the onset of symptoms before a patient sees a healthcare professional and receives a correct diagnosis.1,3-5

Prevalence of Behçet’s Disease

Behçet’s Disease is also known as Silk Road disease because it is commonly found in countries along the ancient network of trade routes between the Mediterranean Sea and Japan, with the highest prevalence in Turkey.5

Estimated prevalence of Behçet’s disease by country2,5,6

Estimated Prevalence of Behçet’s disease per 100,000 people by country2,5,6


-1 per 100,000

People in Austrialia


-1 per 100,000

People in New Zealand


-1 per 100,000

People in China


-1 per 100,000

People in Russia


-1 per 100,000

People in Argentina


-1 per 100,000

People in Chile


-1 per 100,000

People in Brazil


-1 per 100,000

People in Colombia


-1 per 100,000

People in Islands


-1 per 100,000

People in Mexico


0.64 per 100,000

People in UK


1.53 per 100,000

People in Portugal


2.1 per 100,000

People in Kuwait


2.26 per 100,000

People in Germany


3.8 per 100,000

People in Italy


4.9 per 100,000

People in Sweden


5.2 per 100,000

People in US


5.6-7.5 per 100,000

People in Spain


7.1 per 100,000

People in France


7.6 per 100,000

People in Egypt


>15 per 100,000

People in Morocco


17 per 100,000

People in Iraq


20 per 100,000

People in Saudi Arabia


22 per 100,000

People in Japan (Hokkaido)


30.2 per 100,000

People in Korea


80 per 100,000

People in Iran


110 per 100,000

People in Northern China


146.4 per 100,000

People in Israel (Druze)


421 per 100,000

People in Turkey


Newly or rarely reported countries

aDot size reflects prevalence.

Help raise awareness of the
challenges of Behçet’s Disease and reduce the delay in diagnosis

Lack of disease information and awareness are factors that delay the diagnosis of many rare diseases.7 Raising awareness is the logical first step toward improving the lives of people with Behçet’s Disease. Sharing the below information via social media will help raise awareness of Behçet’s Disease and may even prevent a delay in its diagnosis.

Share to Raise Awareness



1. Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P. Behçet’s disease physiopathology: a contemporary review. Auto Immun Highlights. 2016;7(1):4.

2. Cho SB, Cho S, Bang D. New insights in the clinical understanding of Behçet’s disease. Yonsei Med J. 2012;53(1):35-42.

3. Alpsoy E, Donmez L, Onder M, et al. Clinical features and natural course of Behçet’s disease in 661 cases: a multicentre study. Br J Dermatol. 2007;157(5):901-906.

4. American Behçet’s Disease Association website. Accessed October 4, 2018.

5. Leonardo NM, McNeil J. Behçet's disease: is there geographical variation? A review far from the Silk Road. Int J Rheumatol. 2015;2015:945262.

6. Yurdakul S, Yazici Y. Epidemiology of Behçet’s syndrome and regional differences in disease expression. In: Yazici Y, Yazici H, eds. Behçet’s Syndrome. New York, NY: Springer; 2010:35-52.

7. Rare Disorders. Rare Disease Day US. National Organization for Rare Disorders. Accessed November 14, 2018.

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